Series 21, Episode 16 airs Tuesday 16th April at 20:00 on BBC One.

Zosia and Jac’s relationship shows no sign of mending when Jac pulls rank over a patient’s treatment, but when a startling incident forces them to unite, it puts everything into perspective and causes Zosia to reconsider her future at Holby.

A struggling Cameron, already under the watchful eye of Xavier, is put to the test when tasked with treating Xavier’s close relative, but with an erratic patient and a tricky diagnosis, will Cameron be able to handle the pressure?

When Carole arrives at Holby with a sick neighbour she is hopeful it will be an opportunity to make amends with Dom. But as an indifferent Dom tries to keep her at arm’s length it soon becomes clear Carole isn’t going anywhere.